<?xml version="1.0" encoding="UTF-8"?>
<XML><RECORDS>
<RECORD>
	<REFERENCE_TYPE>31</REFERENCE_TYPE>
	<AUTHORS>
		<AUTHOR>Greg Paperin</AUTHOR>
	</AUTHORS>
	<YEAR>2008</YEAR>
	<TITLE>Evolving sequence patterns for prediction of sub-cellular locations of eukaryotic proteins</TITLE>
	<SECONDARY_TITLE>Genetic and Evolutionary Computation Conference 2008 (GECCO&acirc;€™08)</SECONDARY_TITLE>
	<PLACE_PUBLISHED>Atlanta, USA</PLACE_PUBLISHED>
	<PUBLISHER>Association for Computing Machinery</PUBLISHER>
	<PAGES>1135-1136</PAGES>
	<ISBN>978-1-60558-130-9</ISBN>
	<KEYWORDS>
		<KEYWORD>protein</KEYWORD>
		<KEYWORD>localisation,</KEYWORD>
		<KEYWORD>classifier,</KEYWORD>
		<KEYWORD>machine</KEYWORD>
		<KEYWORD>learning,</KEYWORD>
		<KEYWORD>pattern</KEYWORD>
		<KEYWORD>learning</KEYWORD>
	</KEYWORDS>
	<ABSTRACT>A genetic algorithm (GA) is utilised to discover known and novel PROSITE-like sequence templates that can be used to classify the sub-cellular location of eukaryotic proteins. While traditional machine learning techniques present a black-box approach to this problem, the current method explicitly represents the discovered localisation motifs. A combined multi-class location classifier is presented and compared to other techniques based on genetic programming. Without consideration of additional structural information the presented method outperforms the alternative techniques.</ABSTRACT>
	<URL>http://portal.acm.org/citation.cfm?id=1389095.1389315</URL>
</RECORD>
</RECORDS></XML>